Injectable hydrogel-based combination therapy for myocardial infarction: a systematic review and Meta-analysis of preclinical trials.

ABSTRACT:

Introduction

This study evaluates the effectiveness of a combined regimen involving injectable hydrogels for the treatment of experimental myocardial infarction.

Patient concerns

Myocardial infarction is an acute illness that negatively affects quality of life and increases mortality rates. Experimental models of myocardial infarction can aid in disease research by allowing for the development of therapies that effectively manage disease progression and promote tissue repair.

Diagnosis

Experimental animal models of myocardial infarction were established using the ligation method on the anterior descending branch of the left coronary artery (LAD).

Interventions

The efficacy of intracardiac injection of hydrogels, combined with cells, drugs, cytokines, extracellu

SUBMITTER: Gao H 

PROVIDER: S-EPMC10882925 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature