Associations between patterns of blood heavy metal exposure and health outcomes: insights from NHANES 2011-2016.

ABSTRACT:

Background

Extensive research has explored the association between heavy metal exposure and various health outcomes, including malignant neoplasms, hypertension, diabetes, and heart diseases. This study aimed to investigate the relationship between patterns of exposure to a mixture of seven heavy metals and these health outcomes.

Methods

Blood samples from 7,236 adults in the NHANES 2011-2016 studies were analyzed for levels of cadmium, manganese, lead, mercury, selenium, copper, and zinc. Cluster analysis and logistic regression identified three distinct patterns of mixed heavy metal exposure, and their associations with health outcomes were evaluated.

Results

Pattern 1 exhibited higher odds ratios (ORs) for malignancy during NHANES 2011-2012 (OR = 1.33) and 2015-201

SUBMITTER: Wang X 

PROVIDER: S-EPMC10882930 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature