Anion-Binding Properties of Aliphatic Symmetric Squaramide Receptors.

ABSTRACT: Squaramides (SQs), which are very popular for their H-bonding ability, have attracted great interest due to their wide range of applications such as asymmetric synthesis, pharmacology, and anion transportation. In this study, aliphatic symmetric SQs based on cis/trans-1,2-diaminocyclohexane (DACH) substituted with cyclic tertiary amines, synthesized in four steps under simple reaction conditions, were investigated for the first time for their ability to bind Cl^-, Br^-, and I^- anions. The changes in cis/trans geometric isomers and the cyclic ring (pyrrolidine vs piperidine) were found to have a combined effect on the degree of anion binding. The spectroscopic titrations of the SQs with TBA-Cl, TBA-Br, and TBA-I in the range of 0.2

SUBMITTER: Mert S 

PROVIDER: S-EPMC10883022 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature