Tunable Cell-Adhesive Surfaces by Surface-Initiated Photoinduced Electron-Transfer-Reversible Addition-Fragmentation Chain-Transfer Polymerization.

ABSTRACT: Cell adhesion involves many interactions between various molecules on the cell membrane (receptors, coreceptors, integrins, etc.) and surfaces or other cells. Cell adhesion plays a crucial role in the analysis of immune response, cancer treatment, tissue engineering, etc. Cell-cell adhesion can be quantified by measuring cell avidity, which defines the total interaction strength of the live cell binding. Typically, those investigations use tailor-made, reusable chips or surfaces onto which cells are cultured to form a monolayer to which other cells can bind. Cell avidity can then be measured by applying a force and quantifying cell-cell bond ruptures. The subsequent cleaning and reactivation of such biochip and biointeractive surfaces often require repeated etching, leading to device damag

SUBMITTER: Kuzmyn AR 

PROVIDER: S-EPMC10883044 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature