Psychological Distress and the Risk of Adverse Cardiovascular Outcomes in Patients With Coronary Heart Disease.

ABSTRACT:

Background

Psychological distress is a recognized risk factor in patients with coronary heart disease (CHD), but its clinical significance is unclear.

Objectives

The purpose of this study was to determine if an index of psychological distress is independently associated with adverse outcomes and significantly contributes to risk prediction.

Methods

Pooled analysis of 2 prospective cohort studies of patients with stable CHD (N = 891). A psychological distress score was constructed using measures of depression, anxiety, anger, perceived stress, and post-traumatic stress disorder, measured at baseline. The study endpoint included cardiovascular death or first or recurrent nonfatal myocardial infarction or hospitalization for heart failure at 5.9 years.

Results

In

SUBMITTER: Garcia M 

PROVIDER: S-EPMC10883080 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature