Association of coagulation markers with the severity of white matter hyperintensities in cerebral small vessel disease.

ABSTRACT:

Background and purpose

This study aimed to explore the correlation and causal relationship between fibrinogen, D-dimer, and the severity of cerebral white matter hyperintensity (MMH).

Methods

A retrospective analysis of 120 patients with cerebral small vessel disease (CSVD) confirmed by head MRI attending the Third Affiliated Hospital of Beijing University of Traditional Chinese Medicine from August 2021 to February 2023 was performed. According to the Fazekas scale score, the patients were divided into 42 cases in the mild group, 44 cases in the moderate group, and 34 cases in the severe group. The levels of fibrinogen and D-dimer were compared among the three groups; the correlations between fibrinogen, D-dimer, and WMH severity were further analyzed; and independent risk

SUBMITTER: Xu M 

PROVIDER: S-EPMC10883156 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature