Brain Anatomy-Guided MRI Analysis for Assessing Clinical Progression of Cognitive Impairment with Structural MRI.

ABSTRACT: Brain structural MRI has been widely used for assessing future progression of cognitive impairment (CI) based on learning-based methods. Previous studies generally suffer from the limited number of labeled training data, while there exists a huge amount of MRIs in large-scale public databases. Even without task-specific label information, brain anatomical structures provided by these MRIs can be used to boost learning performance intuitively. Unfortunately, existing research seldom takes advantage of such brain anatomy prior. To this end, this paper proposes a brain anatomy-guided representation (BAR) learning framework for assessing the clinical progression of cognitive impairment with T1-weighted MRIs. The BAR consists of a pretext model and a downstream model, with a share

SUBMITTER: Zhang L 

PROVIDER: S-EPMC10883230 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature