Association Between Left Ventricular Scar and Ventricular Ectopy in People Living With and Without HIV.

ABSTRACT:

Background

People living with HIV (PLWH) have greater risk for arrhythmic sudden death and heart failure than people without HIV (PWOH), though risk identifiers remain understudied. Higher ventricular ectopy (VE) burden reflects increased arrhythmic susceptibility and cardiomyopathy risk.

Objectives

The purpose of this study was to test if myocardial scar measured by late gadolinium-enhancement cardiovascular magnetic resonance (LGE-CMR) associates with VE by ambulatory electrocardiographic monitoring among PLWH and PWOH with risk factors for HIV, and if the association differs by HIV.

Methods

Participants from 3 cohorts of PLWH and PWOH underwent electrocardiographic monitoring (median wear time 8.3 days) and CMR. Using multivariable regression, we assessed: 1) assoc

SUBMITTER: Mustapha A 

PROVIDER: S-EPMC10883264 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature