Craving dynamics and related cerebral substrates predict timing of use in alcohol, tobacco, and cannabis use disorders.

ABSTRACT:

Background

Patients treated for Substance Use Disorders exhibit highly fluctuating patterns of craving that could reveal novel prognostic markers of use. Accordingly, we 1) measured fluctuations within intensively repeated measures of craving and 2) linked fluctuations of craving to connectivity indices within resting-state (rs) brain regions to assess their relation to use among patients undergoing treatment for Alcohol, Tobacco and Cannabis Use Disorders.

Method

Participants -64 individuals with SUD for tobacco, alcohol, or cannabis and 35 healthy controls-completed a week of Ecological Momentary Assessment (EMA) during which they reported craving intensity and substance use five times daily. Before EMA, a subsample of 50 patients, and 34 healthy controls also completed re

SUBMITTER: Chirokoff V 

PROVIDER: S-EPMC10883348 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature