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Cognitive impairment in cerebral small vessel disease induced by hypertension.


ABSTRACT:

Abstract

Hypertension is a primary risk factor for the progression of cognitive impairment caused by cerebral small vessel disease, the most common cerebrovascular disease. However, the causal relationship between hypertension and cerebral small vessel disease remains unclear. Hypertension has substantial negative impacts on brain health and is recognized as a risk factor for cerebrovascular disease. Chronic hypertension and lifestyle factors are associated with risks for stroke and dementia, and cerebral small vessel disease can cause dementia and stroke. Hypertension is the main driver of cerebral small vessel disease, which changes the structure and function of cerebral vessels via various mechanisms and leads to lacunar infarction, leukoaraiosis, white matter lesions, and intra

SUBMITTER: Wei W 

PROVIDER: S-EPMC10883517 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature