Pulmonary Alveolar Proteinosis and new therapeutic concepts.

ABSTRACT: Pulmonary alveolar proteinosis (PAP) is an umbrella term used to refer to a pulmonary syndrome which is characterized by excessive accumulation of surfactant in the lungs of affected individuals. In general, PAP is a rare lung disease affecting children and adults, although its prevalence and incidence is variable among different countries. Even though PAP is a rare disease, it is a prime example on how modern medicine can lead to new therapeutic concepts, changing ways and techniques of (genetic) diagnosis which ultimately led into personalized treatments, all dedicated to improve the function of the impaired lung and thus life expectancy and quality of life in PAP patients. In fact, new technologies, such as new sequencing technologies, gene therapy approaches, new kind and sources of st

SUBMITTER: Rodriguez Gonzalez C 

PROVIDER: S-EPMC10883756 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature