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Prognostic value of flow-status in severe aortic stenosis patients undergoing percutaneous intervention.


ABSTRACT:

Purpose

Low-flow status is a mortality predictor in severe aortic stenosis (SAS) patients, including after transcatheter aortic valve implantation (TAVI) treatment. However, the best parameter to assess flow is unknown. Recent studies suggest that transaortic flow rate (FR) is superior to currently used stroke volume index (SVi) in defining low-flow states. Therefore, we aimed to evaluate the prognostic value of FR and SVi in patients undergoing TAVI.

Methods

A single-centre retrospective analysis of all consecutive patients treated with TAVI for SAS between 2011 and 2019 was conducted. Low-FR was defined as < 200 mL/s and low-SVi as < 35 mL/m2. Primary endpoint was all-cause five-year mortality, analyzed using Kaplan-Meier curves and Cox regression models. Second

SUBMITTER: Santos-Ferreira D 

PROVIDER: S-EPMC10884040 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature