BK virus-associated hemorrhagic cystitis in pediatric stem cell transplantation: a case report and scoping review.

ABSTRACT:

Introduction

BK virus-associated hemorrhagic cystitis (BK-HC) is a debilitating and poorly understood complication of hematopoietic stem cell transplantation (SCT). Hematuria, dysuria, and other symptoms associated with BK-HC are common in the immediate post-SCT period, making BK-HC difficult to distinguish from other conditions presenting with these symptoms. Despite published criteria for diagnosis, the degree to which these criteria are consistently applied to either clinical diagnosis or to studies informing BK-HC management is unclear. We present a case of BK-HC in a pediatric SCT recipient, and discuss the challenges associated with treatment in the absence of rigorous data to inform clinical management.

Methods

We reviewed all cases of BK viruria at our center in pati

SUBMITTER: Moss JE 

PROVIDER: S-EPMC10884191 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature