Male spondyloarthritis patients and those with longer disease duration have less severe disc degeneration: propensity score-matched comparison.

ABSTRACT:

Objective

Using whole spine sagittal T2 MRI, we aimed to compare the severity and prevalence of disc degeneration (DD) in axial SpA patients vs the general population and to determine any association between spinal inflammation, structural changes, mobility and DD among SpA patients.

Methods

Two prospectively collected cohorts of SpA patients (n = 411) and the general population (n = 2007) were recruited. Eventually, 967 participants from the populational cohort and 304 participants from the SpA cohort were analysed. Two hundred and nineteen matched pairs were generated by propensity score matching. Imaging parameters, including Pfirrmann grading, disc herniation, high-intensity zone, Schmorl's node, Modic change and anterior marrow change were studied a

SUBMITTER: Cheung STY 

PROVIDER: S-EPMC10884529 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature