Phytosterol intake and risk of coronary artery disease: Results from 3 prospective cohort studies.

ABSTRACT:

Background

Phytosterols are structurally similar to cholesterol and partially inhibit intestinal absorption of cholesterol, although their impact on coronary artery disease (CAD) risk remains to be elucidated.

Objectives

This study aimed to prospectively assess the associations between total and individual phytosterol intake and CAD risk in United States health professionals.

Methods

The analysis included 213,992 participants from 3 prospective cohorts-the Nurses' Health Study (NHS), NHSII, and Health Professionals Follow-Up Study-without cardiovascular disease or cancer at baseline. Diet was assessed using a validated food frequency questionnaire every 2-4 y since baseline. Associations between phytosterol intake and the risk of CAD, such as nonfatal myocardial infar

SUBMITTER: Wang Y 

PROVIDER: S-EPMC10884604 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature