Fe-Zn alloy, a new biodegradable material capable of reducing ROS and inhibiting oxidative stress.

ABSTRACT: Fe-based biodegradable materials have attracted significant attention due to their exceptional mechanical properties and favorable biocompatibility. Currently, research on Fe-based materials mainly focuses on regulating the degradation rate. However, excessive release of Fe ions during material degradation will induce the generation of reactive oxygen species (ROS), leading to oxidative stress and ferroptosis. Therefore, the control of ROS release and the improvement of biocompatibility for Fe-based materials are very important. In this study, new Fe-Zn alloys were prepared by electrodeposition with the intention of using Zn as an antioxidant to reduce oxidative damage during alloy degradation. Initially, the impact of three potential degradation ions (Fe²⁺, Fe³⁺, Zn<

SUBMITTER: Yang S 

PROVIDER: S-EPMC10884730 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature