Arterial Stiffness and Obesity as Predictors of Diabetes: Longitudinal Cohort Study.

ABSTRACT:

Background

Previous studies have confirmed the separate effect of arterial stiffness and obesity on type 2 diabetes; however, the joint effect of arterial stiffness and obesity on diabetes onset remains unclear.

Objective

This study aimed to propose the concept of arterial stiffness obesity phenotype and explore the risk stratification capacity for diabetes.

Methods

This longitudinal cohort study used baseline data of 12,298 participants from Beijing Xiaotangshan Examination Center between 2008 and 2013 and then annually followed them until incident diabetes or 2019. BMI (waist circumference) and brachial-ankle pulse wave velocity were measured to define arterial stiffness abdominal obesity phenotype. The Cox proportional hazard model was used to estimate the hazard r

SUBMITTER: Cui C 

PROVIDER: S-EPMC10884903 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature