Association between frailty and clinical outcomes in patients undergoing craniotomy-systematic review and meta-analysis of observational studies.

ABSTRACT:

Background

Frailty in patients undergoing craniotomy may affect perioperative outcomes. There have been a number of studies published in this field; however, evidence is yet to be summarized in a quantitative review format. We conducted a systematic review and meta-analysis to examine the effects of frailty on perioperative outcomes in patients undergoing craniotomy surgery.

Methods

Our eligibility criteria included adult patients undergoing open cranial surgery. We searched MEDLINE via Ovid SP, EMBASE via Ovid SP, Cochrane Library, and grey literature. We included retrospective and prospective observational studies. Our primary outcome was a composite of complications as per the Clavien-Dindo classification system. We utilized a random-effects model of meta-analysis. We con

SUBMITTER: Licina A 

PROVIDER: S-EPMC10885452 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature