The impact of alternate HPV vaccination and cervical screening strategies in Japan: a cost-effectiveness analysis.

ABSTRACT:

Background

The Japanese 2020 cervical screening guidelines recommend conventional cervical cytology screening every 2-years for women aged 20-69 years. The nonavalent human papillomavirus (HPV) vaccine has also recently been approved in Japan. We therefore evaluated the cost-effectiveness of cervical cancer screening strategies alongside universal nonavalent HPV vaccination of girls (12-16 years).

Methods

A cost-effectiveness analysis was performed using an age-specific Markov microsimulation model for Japan to evaluate total costs, quality adjusted life-years (QALYs) gained, incremental cost-effectiveness ratios (ICER), colposcopies, biopsies, precancer and cervical cancer treatments for 29 combined vaccination and screening strategies (conventional cytology, liquid-based c

SUBMITTER: Palmer MR 

PROVIDER: S-EPMC10885559 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature