Urchin-like multiscale structured fluorinated hydroxyapatite as versatile filler for caries restoration dental resin composites.

ABSTRACT: Caries is one of the most prevalent human diseases, resulting from demineralization of tooth hard tissue caused by acids produced from bacteria, and can progress to pulpal inflammation. Filling restoration with dental resin composites (DRCs) is currently the most common treatment for caries. However, existing DRCs suffer from low fracture strength and lack comprehensive anti-caries bioactivity including remineralization, pulp protection, and anti-cariogenic bacteria effects. In this study, inspired by plant roots' ability to stabilize and improve soil, fluorinated urchin-like hydroxyapatite (FUHA) with a three-dimensional whisker structure and bioactive components of calcium, phosphorus, and fluorine was designed and synthesized by a dynamic self-assembly method. Furthermore, versatile FUH

SUBMITTER: Zhang S 

PROVIDER: S-EPMC10885616 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature