Stereotactic body radiotherapy of central lung tumours using a 1.5 T MR-linac: First clinical experiences.

ABSTRACT:

Background

MRI-guidance may aid better discrimination between Organs at Risk (OARs) and target volumes in proximity of the mediastinum. We report the first clinical experiences with Stereotactic Body Radiotherapy (SBRT) of (ultra)central lung tumours on a 1.5 T MR-linac.

Materials and methods

Patients with an (ultra)central lung tumour were selected for MR-linac based SBRT treatment. A T2-weighted 3D sequence MRI acquired during free breathing was used for daily plan adaption. Prior to each fraction, contours of Internal Target Volume (ITV) and OARs were deformably propagated and amended by a radiation oncologist. Inter-fractional changes in volumes and coverage of target volumes as well as doses in OARs were evaluated in offline and online treatment plans.

Results

Te

SUBMITTER: Merckel LG 

PROVIDER: S-EPMC10885732 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature