Estradiol associations with brain functional connectivity in postmenopausal women.

ABSTRACT:

Objective

Previous studies have found that estrogens play a role in functional connectivity in the brain; however, little research has been done regarding how estradiol is associated with functional connectivity in postmenopausal women. The purpose of this study was to examine the relationship between estradiol and functional connectivity in postmenopausal women.

Methods

Structural and blood oxygenation level-dependent resting-state magnetic resonance imaging scans of 88 cognitively healthy postmenopausal individuals were obtained along with blood samples collected the same day as the magnetic resonance imaging to assess hormone levels. We generated connectivity values in CONN toolbox version 20.b, an SPM-based software.

Results

A regression analysis was run using est

SUBMITTER: Testo AA 

PROVIDER: S-EPMC10885742 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature