Comparable Toxicity of Surface-Modified TiO₂ Nanoparticles: An In Vivo Experimental Study on Reproductive Toxicity in Rats.

ABSTRACT: Nanoparticles (NPs), a distinct class of particles ranging in size from 1 to 100 nm, are one of the most promising technologies of the 21st century, and titanium dioxide NPs (TiO₂ NPs) are among the most widely produced and used NPs globally. The increased application of TiO₂ NPs raises concerns regarding their global safety and risks of exposure. Many animal studies have reported the accumulation of TiO₂ NPs in female reproductive organs; however, evidence of the resultant toxicity remains ambiguous. Since the surface area and chemical modifications of NPs can significantly change their cytotoxicity, we aimed to compare the toxic effects of pristine TiO₂ powder with surface-modified TiO₂ powders with salicylic acid (TiO₂/SA

SUBMITTER: Todorovic A 

PROVIDER: S-EPMC10886084 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature