3D Printed Piezoelectric BaTiO₃/Polyhydroxybutyrate Nanocomposite Scaffolds for Bone Tissue Engineering.

ABSTRACT: Bone defects are a significant health problem worldwide. Novel treatment approaches in the tissue engineering field rely on the use of biomaterial scaffolds to stimulate and guide the regeneration of damaged tissue that cannot repair or regrow spontaneously. This work aimed at developing and characterizing new piezoelectric scaffolds to provide electric bio-signals naturally present in bone and vascular tissues. Mixing and extrusion were used to obtain nanocomposites made of polyhydroxybutyrate (PHB) as a matrix and barium titanate (BaTiO₃) nanoparticles as a filler, at BaTiO₃/PHB compositions of 5/95, 10/90, 15/85 and 20/80 (w/w%). The morphological, thermal, mechanical and piezoelectric properties of the nanocomposites were studied. Scanning electron microscopy anal

SUBMITTER: Strangis G 

PROVIDER: S-EPMC10886384 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature