Cellular Senescence, Mitochondrial Dysfunction, and Their Link to Cardiovascular Disease.

ABSTRACT: Cardiovascular diseases (CVDs), a group of disorders affecting the heart or blood vessels, are the primary cause of death worldwide, with an immense impact on patient quality of life and disability. According to the World Health Organization, CVD takes an estimated 17.9 million lives each year, where more than four out of five CVD deaths are due to heart attacks and strokes. In the decades to come, an increased prevalence of age-related CVD, such as atherosclerosis, coronary artery stenosis, myocardial infarction (MI), valvular heart disease, and heart failure (HF) will contribute to an even greater health and economic burden as the global average life expectancy increases and consequently the world's population continues to age. Considering this, it is important to focus our research effo

SUBMITTER: Camacho-Encina M 

PROVIDER: S-EPMC10886919 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature