Development and Comparison of Treatment Decision Tools for Glucocorticoid-Induced Osteoporosis.

ABSTRACT: Long-term Glucocorticoid (GC) use results in compromised bone strength and fractures, and several treatment recommendations have been developed to prevent fractures, but none have been validated in a real-world setting. This study aims to create a treatment decision tool and compares this tool to the treatment suggestions from the American College of Rheumatology (ACR), International Osteoporosis Foundation and European Calcified Tissue Society (IOF-ECTS), and GC-adjusted Fracture Risk Assessment Tool (GC-FRAX), above the intervention threshold. We utilized registry data gathered at Chang Gung Memorial Hospital at Kaohsiung, Taiwan, between September 2015 and April 2021. This research is a single-center, observational, and case-controlled study. We recruited participants using prednisone f

SUBMITTER: Chen JF 

PROVIDER: S-EPMC10887529 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature