Segregated Dynamical Networks for Biological Motion Perception in the Mu and Beta Range Underlie Social Deficits in Autism.

ABSTRACT:

Objective

Biological motion perception (BMP) correlating with a mirror neuron system (MNS) is attenuated in underage individuals with autism spectrum disorder (ASD). While BMP in typically-developing controls (TDCs) encompasses interconnected MNS structures, ASD data hint at segregated form and motion processing. This coincides with less fewer long-range connections in ASD than TDC. Using BMP and electroencephalography (EEG) in ASD, we characterized directionality and coherence (mu and beta frequencies). Deficient BMP may stem from desynchronization thereof in MNS and may predict social-communicative deficits in ASD. Clinical considerations thus profit from brain-behavior associations.

Methods

Point-like walkers elicited BMP using 15 white dots (walker vs. scramble in 21 ASD

SUBMITTER: Siemann J 

PROVIDER: S-EPMC10887711 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature