Radioactive Seed Localization for Nonpalpable Breast Lesions: Systematic Review and Meta-Analysis.

ABSTRACT:

Background

This study is a systematic review with meta-analysis comparing radioactive seed localization (RSL) versus radio-guided occult lesion localization (ROLL) and wire-guided localization (WGL) for patients with impalpable breast cancer undergoing breast-conserving surgery and evaluating efficacy, safety, and logistical outcomes. The protocol is registered in PROSPERO with the number CRD42022299726.

Methods

A search was conducted in the Embase, Lilacs, Pubmed, Scielo, Web of Science, and clinicaltrials.gov databases, in addition to a manual search in the reference list of relevant articles, for randomized clinical trials and cohort studies. Studies selected were submitted to their own data extraction forms and risk of bias analysis according to the ROB 2 and ROBINS 1 to

SUBMITTER: Ferreira HHJ 

PROVIDER: S-EPMC10887864 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature