A Real-World Retrospective Analysis of the Management of Advanced Urothelial Carcinoma in Canada.

ABSTRACT: Locally advanced or metastatic urothelial carcinoma (aUC) presents a significant challenge with high mortality rates. Platinum-based chemotherapy remains the established frontline standard of care, and a switch-maintenance strategy with immunotherapy has now emerged as a new standard for aUC patients without disease progression, following initial platinum therapy. Examining the treatment patterns is imperative, given the evolving therapeutic landscape. In this study, we conducted a retrospective medical chart review of 17 Canadian oncologists treating patients with aUC to assess unmet needs in Canadian aUC patient care. Data from 146 patient charts were analyzed, revealing important clinical insights about the management of aUC. A substantial proportion of patients (53%) presented with de

SUBMITTER: Moria FA 

PROVIDER: S-EPMC10887988 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature