BCG and Alternative Therapies to BCG Therapy for Non-Muscle-Invasive Bladder Cancer.

ABSTRACT: Bladder cancer is a heterogeneous disease. Treatment decisions are mostly decided based on disease stage (non-muscle invasive or muscle invasive). Patients with muscle-invasive disease will be offered a radical treatment combined with systemic therapy, while in those with non-muscle-invasive disease, an attempt to resect the tumor endoscopically will usually be followed by different intravesical instillations. The goal of intravesical therapy is to decrease the recurrence and/or progression of the tumor. In the current landscape of bladder cancer treatment, BCG is given intravesically to induce an inflammatory response and recruit immune cells to attack the malignant cells and induce immune memory. While the response to BCG treatment has changed the course of bladder cancer management and

SUBMITTER: Lidagoster S 

PROVIDER: S-EPMC10888316 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature