Unknown

Dataset Information

0

Artificial Intelligence-Enhanced Quantitative Ultrasound for Breast Cancer: Pilot Study on Quantitative Parameters and Biopsy Outcomes.


ABSTRACT: Traditional B-mode ultrasound has difficulties distinguishing benign from malignant breast lesions. It appears that Quantitative Ultrasound (QUS) may offer advantages. We examined the QUS imaging system's potential, utilizing parameters like Attenuation Coefficient (AC), Speed of Sound (SoS), Effective Scatterer Diameter (ESD), and Effective Scatterer Concentration (ESC) to enhance diagnostic accuracy. B-mode images and radiofrequency signals were gathered from breast lesions. These parameters were processed and analyzed by a QUS system trained on a simulated acoustic dataset and equipped with an encoder-decoder structure. Fifty-seven patients were enrolled over six months. Biopsies served as the diagnostic ground truth. AC, SoS, and ESD showed significant differences between benign and malignant lesions (p < 0.05), but ESC did not. A logistic regression model was developed, demonstrating an area under the receiver operating characteristic curve of 0.90 (95% CI: 0.78, 0.96) for distinguishing between benign and malignant lesions. In conclusion, the QUS system shows promise in enhancing diagnostic accuracy by leveraging AC, SoS, and ESD. Further studies are needed to validate these findings and optimize the system for clinical use.

SUBMITTER: Kwon H 

PROVIDER: S-EPMC10888332 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature

altmetric image

Publications

Artificial Intelligence-Enhanced Quantitative Ultrasound for Breast Cancer: Pilot Study on Quantitative Parameters and Biopsy Outcomes.

Kwon Hyuksool H   Oh Seokhwan S   Kim Myeong-Gee MG   Kim Youngmin Y   Jung Guil G   Lee Hyeon-Jik HJ   Kim Sang-Yun SY   Bae Hyeon-Min HM  

Diagnostics (Basel, Switzerland) 20240214 4


Traditional B-mode ultrasound has difficulties distinguishing benign from malignant breast lesions. It appears that Quantitative Ultrasound (QUS) may offer advantages. We examined the QUS imaging system's potential, utilizing parameters like Attenuation Coefficient (AC), Speed of Sound (SoS), Effective Scatterer Diameter (ESD), and Effective Scatterer Concentration (ESC) to enhance diagnostic accuracy. B-mode images and radiofrequency signals were gathered from breast lesions. These parameters w  ...[more]

Similar Datasets

| S-EPMC10294449 | biostudies-literature
| S-EPMC11751672 | biostudies-literature
| S-EPMC10625864 | biostudies-literature
| S-EPMC4763162 | biostudies-other
| S-EPMC11904735 | biostudies-literature
| S-EPMC9275035 | biostudies-literature
| S-EPMC10759705 | biostudies-literature
| S-EPMC8463596 | biostudies-literature
| S-EPMC10173041 | biostudies-literature
| S-EPMC9258019 | biostudies-literature