Antineoplastic Activity of 9″-Lithospermic Acid Methyl Ester in Glioblastoma Cells.

ABSTRACT: To date, many potent compounds have been found which are derived from plants and herbs and possess anticancer properties due to their antioxidant effects. 9″-Lithospermic acid methyl ester is an effective natural compound derived from the Thymus thracicus Velen. It has been proven that this compound has substantial properties in different diseases, but its effects in cancer have not been thoroughly evaluated. The aim of this work was to study the effects of 9″-Lithospermic acid methyl ester (9″-methyl lithospermate) in U87 and T98 glioblastoma cell lines. Its effects on cellular viability were assessed via Trypan Blue and Crystal Violet stains, the cell cycle analysis through flow cytometry, and cell migration by employing the scratch wound healing assay. The results demonstrated th

SUBMITTER: Tzitiridou P 

PROVIDER: S-EPMC10889145 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature