Chemical Analysis and Biological Activities of Extracts Isolated from Symbiotic L. japonicus Plants.

ABSTRACT: Plants produce a wide variety of secondary metabolites, including compounds with biological activities that could be used for the treatment of human diseases. In the present study, we examined the putative production of bioactive molecules in the legume plant Lotus japonicus, which engages into symbiotic relationships with beneficial soil microorganisms. To monitor the production of secondary metabolites when the plant develops beneficial symbiotic relationships, we performed single and double inoculations with arbuscular mycorrhizal fungi (AMF) and nitrogen-fixing Rhizobium bacteria. Plant extracts from non-inoculated and inoculated plants were chemically characterized and tested for anti-proliferative, apoptotic, and anti-inflammatory effects on human HEK-293 cells. Both sh

SUBMITTER: Kalousi FD 

PROVIDER: S-EPMC10889931 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature