Chronic Toxoplasma gondii Infection Modulates Hearing Ability across the Adult Life Span.

ABSTRACT: While several studies have shown associations between hearing disorders and congenital toxoplasmosis, the present study investigated the impact of chronic, latent Toxoplasma gondii (T. gondii) infection on hearing loss. We used a regression analysis to explore whether latent T. gondii infection modulates changes in hearing thresholds over an age range from 20 to 70 years. We analyzed audiometric data of 162 T. gondii IgG-positive and 430 T. gondii-negative participants, collected in the Dortmund Vital Study (DVS, ClinicalTrials.gov Identifier: NCT05155397), a prospective study on healthy cognitive aging. The regression analysis indicated that latent toxoplasmosis was associated with an accelerated development in hearing loss over the observed age range. H

SUBMITTER: Getzmann S 

PROVIDER: S-EPMC10890099 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature