Urinary Metabolomic Differentiation of Infants Fed on Human Breastmilk and Formulated Milk.

ABSTRACT: Human breastmilk is an invaluable nutritional and pharmacological resource with a highly diverse metabolite profile, which can directly affect the metabolism of infants. Application of metabolomics can discriminate the complex relationship between such nutrients and infant health. As the most common biological fluid in metabolomic study, infant urinary metabolomics may provide the physiological impacts of different nutritional resources, namely human breastmilk and formulated milk. In this study, we aimed to identify possible differences in the urine metabolome of 30 infants (1-14 days after birth) fed with breast milk (n = 15) or formulated milk (n = 15). From metabolomic analysis with gas chromatography-mass spectrometry, 163 metabolites from single mass spectrometry (GC-MS

SUBMITTER: Yu JW 

PROVIDER: S-EPMC10890188 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature