Lung cancer in females-sex-based differences from males in epidemiology, biology, and outcomes: a narrative review.

ABSTRACT:

Background and objective

The role of biological sex is seldom considered in characterizing lung cancer, the deadliest cancer in both the United States and the world. Lung cancer has traditionally been regarded as a male disease; as such, research in female-specific phenomena is frequently conflicting or absent. Currently, disparities in lung cancer incidence are primarily driven by females, especially non-smokers and those of younger age. This narrative review provides insight into sex-specific characteristics of lung cancer, highlighting risk factors, diagnosis patterns, carcinogenesis, and treatment outcomes in females.

Methods

The PubMed database was searched on July 26, 2023 to identify research published between 2013 and 2023 in English. Sixty-three articles were consid

SUBMITTER: Gee K 

PROVIDER: S-EPMC10891406 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature