Cocaine use and head and neck cancer risk: A pooled analysis in the International Head and Neck Cancer Epidemiology Consortium.

ABSTRACT:

Background

Cocaine is an illegal recreational drug used worldwide, yet little is known about whether cocaine inhalation (smoking/snorting) increases the risk of head and neck cancer (HNC).

Methods

The analyses were conducted by pooling data from three case-control studies with 1639 cases and 2506 controls from the International Head and Neck Cancer Epidemiology Consortium. Epidemiologic data, including cocaine use histories, were obtained in face-to-face interviews. Odds ratios (ORs) and corresponding 95% confidence intervals (CIs) were estimated using hierarchical logistic regression models.

Results

Controlling for cumulative tobacco and alcohol use, we observed a weak positive association between cocaine use and HNC (OR_{ever vs. never}  = 1.35, 95% CI: 0.96

SUBMITTER: Zhang M 

PROVIDER: S-EPMC10891447 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature