Major Adverse Kidney Events in Pediatric Continuous Kidney Replacement Therapy.

ABSTRACT:

Importance

Continuous kidney replacement therapy (CKRT) is increasingly used in youths with critical illness, but little is known about longer-term outcomes, such as persistent kidney dysfunction, continued need for dialysis, or death.

Objective

To characterize the incidence and risk factors, including liberation patterns, associated with major adverse kidney events 90 days after CKRT initiation (MAKE-90) in children, adolescents, and young adults.

Design, setting, and participants

This international, multicenter cohort study was conducted among patients aged 0 to 25 years from The Worldwide Exploration of Renal Replacement Outcomes Collaborative in Kidney Disease (WE-ROCK) registry treated with CKRT for acute kidney injury or fluid overload from 2015 to 2021. Exclusi

SUBMITTER: Fuhrman DY 

PROVIDER: S-EPMC10891477 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature