Lactobacilli in COVID-19: A Systematic Review Based on Next-Generation Sequencing Studies.

ABSTRACT: The global pandemic was caused by the SARS-CoV-2 virus, known as COVID-19, which primarily affects the respiratory and intestinal systems and impacts the microbial communities of patients. This systematic review involved a comprehensive search across the major literature databases to explore the relationship between lactobacilli and COVID-19. Our emphasis was on investigations employing NGS technologies to explore this connection. Our analysis of nine selected studies revealed that lactobacilli have a reduced abundance in the disease and an association with disease severity. The protective mechanisms of lactobacilli in COVID-19 and other viral infections are likely to be multifaceted, involving complex interactions between the microbiota, the host immune system, and the virus itself. Moreo

SUBMITTER: Taufer CR 

PROVIDER: S-EPMC10891515 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature