Pyrrole Compounds from the Two-Step One-Pot Conversion of 2,5-Dimethylfuran for Elastomer Composites with Low Dissipation of Energy.

ABSTRACT: A one-pot, two-step process was developed for the preparation of pyrrole compounds from 2,5-dimethylfuran. The first step was the acid-catalyzed ring-opening reaction of 2,5-dimethylfuran (DF), leading to the formation of 2,5-hexanedione (HD). A stoichiometric amount of water and a sub-stoichiometric amount of sulfuric acid were used by heating at 50 °C for 24 h. Chemically pure HD was isolated, with a quantitative yield (up to 95%), as revealed by ¹H-NMR, ¹³C-NMR, and GC-MS analyses. In the second step, HD was used as the starting material for the synthesis of pyrrole compounds via the Paal-Knorr reaction. Various primary amines were used in stoichiometric amounts. ¹H-NMR, ¹³C-NMR, ESI-Mass, and GC-Mass analyses confirmed that pyrrole compounds

SUBMITTER: Naddeo S 

PROVIDER: S-EPMC10891845 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature