Anti-Cariogenic Effects of <i>S. cerevisiae</i> and <i>S. boulardii</i> in <i>S. mutans-C. albicans</i> Cross-Kingdom In Vitro Models.

ABSTRACT: Despite the well-documented health benefits of the probiotic Saccharomyces, its application in oral health has not been comprehensively assessed. Dental caries is a transmissible disease initiated by acid production of cariogenic bacteria and yeast, such as Streptococcus mutans and Candida albicans, on tooth enamel and followed by subsequent enamel demineralization. Here, we investigated the effect of two Saccharomyces strains (Saccharomyces boulardii and Saccharomyces cerevisiae) on S. mutans-C. albicans cross-kingdom interactions using a cariogenic planktonic model. Viable cells, pH changes, and gene expression were measured. S. cerevisiae and S. boulardii inhibited the growth of C. albicans in dual- and multi-s

SUBMITTER: Yousif D 

PROVIDER: S-EPMC10891968 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature