Biotechnological Production and Characterization of Extracellular Melanin by Streptomyces nashvillensis.

ABSTRACT: Melanins are pigments employed in food, cosmetic, and textile industries, manufactured by extraction from cuttlefishes. Their biotechnological production by Streptomycetes, instead, has been poorly investigated so far. In this paper, for the first time, the strain Streptomyces nashvillensis DSM 40314 was tested as an extracellular melanin producer by investigating the influence of diverse temperatures (26, 28, and 30 °C) and pH values (6.0 and 7.0) on bacterial growth, melanin production, and on the activity of the secreted tyrosinase, the first enzyme of the pigment biosynthetic pathway. In physiological 96-h shake flask experiments, the optimal growth parameters resulted to be 28 °C and pH 7.0, at which a maximum biomass of 8.4 ± 0.5 g_cdw/L, a melanin concentration of 0

SUBMITTER: Restaino OF 

PROVIDER: S-EPMC10892051 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature