Planimetric and Volumetric Brainstem MRI Markers in Progressive Supranuclear Palsy, Multiple System Atrophy, and Corticobasal Syndrome. A Systematic Review and Meta-Analysis.

ABSTRACT:

Background

Various MRI markers-including midbrain and pons areas (M_area, P_area) and volumes (M_vol, P_vol), ratios (M/P_area, M/P_vol), and composite markers (magnetic resonance imaging Parkinsonism Indices 1,2; MRPI 1,2)-have been proposed as imaging markers of Richardson's syndrome (RS) and multiple system atrophy-Parkinsonism (MSA-P). A systematic review/meta-analysis of relevant studies aiming to compare the diagnostic accuracy of these imaging markers is lacking.

Methods

Pubmed and Scopus were searched for studies with >10 patients (RS, MSA-P or CBS) and >10 controls with data on M_area, P_area, M_vol, P_vol, M/P_area, M/P_vol, MRPI 1, and MRPI 2. Co

SUBMITTER: Brinia ME 

PROVIDER: S-EPMC10892270 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature