Bacterial Efflux Pump Inhibitors Reduce Antibiotic Resistance.

ABSTRACT: Bacterial resistance is a growing problem worldwide, and the number of deaths due to drug resistance is increasing every year. We must pay great attention to bacterial resistance. Otherwise, we may go back to the pre-antibiotic era and have no drugs on which to rely. Bacterial resistance is the result of several causes, with efflux mechanisms widely recognised as a significant factor in the development of resistance to a variety of chemotherapeutic and antimicrobial medications. Efflux pump inhibitors, small molecules capable of restoring the effectiveness of existing antibiotics, are considered potential solutions to antibiotic resistance and have been an active area of research in recent years. This article provides a review of the efflux mechanisms of common clinical pathogenic bacteria

SUBMITTER: Zhang L 

PROVIDER: S-EPMC10892612 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature