Usefulness of ¹⁸F-FDG PET-CT in the Management of Febrile Neutropenia: A Retrospective Cohort from a Tertiary University Hospital and a Systematic Review.

ABSTRACT: Febrile neutropenia (FN) is a complication of hematologic malignancy therapy. An early diagnosis would allow optimization of antimicrobials. The ¹⁸F-FDG-PET-CT may be useful; however, its role is not well established. We analyzed retrospectively patients with hematological malignancies who underwent ¹⁸F-FDG-PET-CT as part of FN management in our university hospital and compared with conventional imaging. In addition, we performed a systematic review of the literature assessing the usefulness of ¹⁸F-FDG-PET-CT in FN. A total of 24 cases of FN underwent ¹⁸F-FDG-PET-CT. In addition, 92% had conventional CT. In 5/24 episodes (21%), the fever was of infectious etiology: two were bacterial, two were fungal, and one was parasitic. When compared with con

SUBMITTER: Gutierrez-Villanueva A 

PROVIDER: S-EPMC10893204 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature