Characterization of resistance genes and replicon typing in Carbapenem-resistant Klebsiella pneumoniae strains.

ABSTRACT:

Objective

In our study, K. pneumoniae strains (non-susceptible to carbapenem) (n = 60) were obtained from various clinical samples from Rize State Hospital between 2015 and 2017 and it is aimed to identify antibiotic resistance genes and replicon typing.

Methods

Antibiotic susceptibility tests of the strains were performed with Kirby-Bauer disk diffusion test and the Vitek-2 automated system (BioMerieux, France). Antibiotic resistance genes and replicon typing was characterized by PCR method.

Results

It was determined that K. pneumaniae isolates were mostly isolated from the samples of the intensive care unit. All of the K. pneumoniae strains examined in this study were found to be ampicillin/sulbactam and ertapenem resistant but colistin susceptible. Amoxacillin/clav

SUBMITTER: Karaman E 

PROVIDER: S-EPMC10893597 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature