Phenotypes of osteoarthritis-related knee pain and their transition over time: data from the osteoarthritis initiative.

ABSTRACT:

Background

Identification of knee osteoarthritis (OA) pain phenotypes, their transition patterns, and risk factors for worse phenotypes, may guide prognosis and targeted treatment; however, few studies have described them. We aimed to investigate different pain phenotypes, their transition patterns, and potential risk factors for worse pain phenotypes.

Methods

Utilizing data from the Osteoarthritis Initiative (OAI), pain severity was assessed using the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) pain subscale. We identified the activity-related pain phenotypes and estimated the transition probabilities of pain phenotypes from baseline to the 24-month using latent transition analysis. We examined the risk factors at baseline with the 24-month pain p

SUBMITTER: Ye J 

PROVIDER: S-EPMC10893610 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature