Effectiveness of azvudine in reducing mortality of COVID-19 patients: a systematic review and meta-analysis.

ABSTRACT:

Background

Azvudine has been approved for the treatment of coronavirus disease 2019 (COVID-19) patients in China, and this meta-analysis aims to illustrate the safety of azvudine and its effectiveness in reducing mortality.

Methods

PubMed, Embase, Web of science, Cochrane Library and the Epistemonikos COVID-19 Living Overview of Evidence database (L.OVE) were searched to aggregate currently published studies. Cochrane risk of bias tool and ROBINS-I tool were used to assess the risk of bias of randomized controlled study and cohort study respectively. Odds radios (ORs) with 95% confidence interval (CIs) were combined for dichotomous variables. Publication bias was assessed by Egger's test and funnel plots.

Results

A total of 184 articles were retrieved from the include

SUBMITTER: Wang Y 

PROVIDER: S-EPMC10893615 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature