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Urokinase in the treatment of tuberculous pleurisy: a systematic review and meta-analysis.


ABSTRACT:

Objective

To evaluate the efficacy of urokinase (UK) treatment for tuberculous pleural effusion (TPE).

Methods

We searched Chinese biomedical literature database, WanFang data, CNKI, PubMed, EMbase, Web of Science and The Cochrane Library for the randomized controlled trials (RCTs) of urokinase treatment for tuberculous pleurisy from January 2000 to February 2023. Pleural tuberculosis, urokinase and randomized controlled trial were used as keywords. The eligible studies were meta-analyzed by using Revman 5.4.1: risk of bias was assessed, mean difference (MD) and 95% CI were used for continuous variables, pooled studies were conducted using random-effects or fixed-effects models, forest plots were drawn to analyze efficacy, and funnel plots were drawn to discuss publication b

SUBMITTER: Jing W 

PROVIDER: S-EPMC10893646 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature