Insulin resistance and coronary inflammation in patients with coronary artery disease: a cross-sectional study.

ABSTRACT:

Background

Insulin resistance (IR) is associated with coronary artery disease (CAD) severity. However, its underlying mechanisms are not fully understood. Therefore, our study aimed to explore the relationship between IR and coronary inflammation and investigate the synergistic and mediating effects of coronary inflammation on the association between IR and CAD severity.

Methods

Consecutive patients with CAD who underwent coronary angiography and coronary computed tomography angiography between April 2018 and March 2023 were enrolled. The triglyceride-glucose index (TyG index) and peri-coronary adipose tissue (PCAT) attenuation around the proximal right coronary artery (RCA) were used to evaluate IR and coronary inflammation, respectively. The correlation between the TyG ind

SUBMITTER: Yang T 

PROVIDER: S-EPMC10893710 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature